Frost.com - Healthcare Research http://www.frost.com/c/10024/home.do - Healthcare Research Thu, 19 Oct 2017 17:26:50 Innovative Solutions for Drug Discovery and Development http://www.frost.com/prod/servlet/sublib/display-report.do?id=D951-00-16-00-00 This Drug Discovery TechVision Opportunity Engine (TOE) provides insights across novel methods that improve drug discovery. The service encompasses recent advances in drug discovery technologies that impact precision oncology, targeted cancer therapy, Big Data analytics and Parkinson s disease management. Lastly, the TOE summarizes key technology trends that leverage stem cell platforms for advancing drug discovery. The Drug Discovery TechVision Opportunity Engine (TOE) reports and analyzes about the latest developments in drug discovery and therapeutics, thereby providing an opportunity to acquire strategic insights into crucial developments in this industry domain. Technologies profiled include those used for biomarker and target discovery such as high throughput screening, signal transduction, micro array, RNAi, metabolomics, toxicogenomics, biosensors and nanotechnology. In addition to these, a fair focus shall be dedicated to the latest trends in therapeutic approaches across a diversity of diseases including infectious, genetic, metabolic, neurological, cardiac, and autoimmune disorders. The Health and Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Drug discovery, biofluorescence, cancer detection, genome analytics, precision oncology, Big Data analytics, cancer vaccines, cancer biosimilar, Parkinson s disease, non-small cell lung cancer (NSCLC), NR0B1, NR0B1, induced pluripotent stem cell (iPSC) Fri, 13 Oct 2017 00:00:00 +0100 Recent Advances in Lab-on-a-Chip and Tissue Repair Technologies http://www.frost.com/prod/servlet/sublib/display-report.do?id=D758-00-5C-00-00 This edition of the Genetic Technology TOE depicts the current landscape and the new life sciences trends across lab-on-chip technology and tissue repair engineering. Particular focus is on advanced microfluidics and wound healing. The corresponding clinical trials scenario is depicted, along with the industry interactions. The Genetic Technology TechVision Opportunity Engine (TOE) presents the latest R&D developments and advances with an emphasis on opportunities to profit in the explosive field of genetic technology through technology transfer, joint ventures, and acquisitions. The complete gamut of genetic technology applications is covered including the latest developments in omics technologies; genetic, cellular, and alternative therapies; sequencing technologies; and genetically altered animals and plants. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Microfluidics, wound healing, lab-on-a-chip, tissue engineering, tissue repair, 3D printing, nanotechnology, skin regeneration, point-of-care devices Fri, 13 Oct 2017 00:00:00 +0100 An End User Perspective on Navigating Digital Transformation, Healthcare, Global, 2017 http://www.frost.com/prod/servlet/sublib/display-report.do?id=K239-01-00-00-00 The overall research objective is to measure the current use and future decision making behavior toward information technology (IT) in the healthcare industry around the globe, specifically: Enterprise Mobility Management, eCommerce/mCommerce, Unified Communications & Collaboration (UCC), Infrastructure and Data Centers, Big Data and Analytics, Omnichannel Marketing, Customer Experience Management, Cyber Security, Internet of Things, Enterprise Content and Business Processes Management, Fintech, and API/CPaaS (Application Programming Interface/Communications Platforms as a Service) Strategy. Frost & Sullivan aims to: Understand the IT-related challenges organizations face today Monitor the status of digital transformation including newer solutions such as Artificial Intelligence (AI), Augmented Reality/Virtual Reality (AR/VR), and mCommerce Assess the current and future use of business communications technologies Evaluate factors that drive investments in communications technologies Gauge IT and communications trends Appraise available IT budgets Healthcare s top IT challenge is different from other industries 34% of respondents find that systems integration and managing multi-vendor solutions is the biggest concern. Dealing with security concerns in second place (26%), followed by ensuring network stability/reliability (26%). Most other industries claim security is their biggest challenge. Technologies that have the most impact on revenue growth in healthcare are cyber security, big data and analytics, and data centers. Respondents who have invested in IoT find that its top benefits include the ability to boost customer service/marketing, improve employee safety, collect customer usage data, and optimize field or on-site operations. When asked the question how critical are the following investments for your organization's digital transformation success over the next 5 years, data analytics and communications/collaboration tools integration with other business software (Microsoft Office, Google G-suite, CRM, ERP, vertical apps) came out ahead. With healthcare in a period of changing regulations, new and innovative procedures, drugs, and devices, and political uncertainty, and effective digital transformation will be crucial across the industry. Mon, 9 Oct 2017 00:00:00 +0100 Recent Advances in Biologic Treatments http://www.frost.com/prod/servlet/sublib/display-report.do?id=D758-00-5B-00-00 This edition of the Genetic Technology TOE depicts the current landscape and the new life sciences trends across biologic treatments. In particular, proteomic and microbiome therapies are profiled. The corresponding clinical trials scenario for individualized cancer therapies is depicted, along with industry interactions. The Genetic Technology TechVision Opportunity Engine (TOE) presents the latest R&D developments and advances with an emphasis on opportunities to profit in the explosive field of genetic technology through technology transfer, joint ventures, and acquisitions. The complete gamut of genetic technology applications is covered including the latest developments in omics technologies; genetic, cellular, and alternative therapies; sequencing technologies; and genetically altered animals and plants. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Proteomics, microbiome, liquid biopsy, cancer immunotherapy, genomically recoding bacteria, therapeutic proteins, Caplacizumab, SER-287 Fri, 6 Oct 2017 00:00:00 +0100 Recent Advances in Genetic Technologies http://www.frost.com/prod/servlet/sublib/display-report.do?id=D758-00-5A-00-00 This edition of the Genetic Technology TOE depicts the current landscape and the new life sciences trends across genetic technologies, especially nucleic acid engineering platforms including gene editing. The corresponding clinical trials scenario regarding multiple sclerosis is depicted, along with the industry interactions. The Genetic Technology TechVision Opportunity Engine (TOE) presents the latest R&D developments and advances with an emphasis on opportunities to profit in the explosive field of genetic technology through technology transfer, joint ventures, and acquisitions. The complete gamut of genetic technology applications is covered including the latest developments in omics technologies; genetic, cellular, and alternative therapies; sequencing technologies; and genetically altered animals and plants. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Nucleic acid engineering platforms, CRSIPR, gene editing, human embryogenesis, mRNA delivery, multiple sclerosis, tri-specific antibody platform, HIV/AIDS management Fri, 29 Sep 2017 00:00:00 +0100 Advances in Clinical Workflow Automation, GI Imaging, Machine Learning Solution for Stroke Treatment, High-Frequency Ultrasound, AI-enabled Diagnostic Imaging http://www.frost.com/prod/servlet/sublib/display-report.do?id=D861-00-18-00-00 The latest issue of Medical and Diagnostic Imaging TechVision Opportunity Engine (TOE) profiles innovations in medical and diagnostic imaging. Some of the profiles covered include an artificial intelligence-based solution for automating clinical workflow, quadripolar MRI compatible CRT leads, GI anatomical and functional imaging, a brain blood flow monitoring device, a machine learning solution for stroke treatment, a portable vein viewing imaging device, and high-frequency ultrasound for glaucoma treatment. Medical and Diagnostic Imaging TechVision Opportunity Engine (TOE)'s mission is to analyze and report new and emerging technologies; advances in R&D, product development and regulatory matters specifically related to the areas of CT, MRI, NM, PET, Ultrasound and X-ray. In addition, relevant developments in fusion technologies, functional imaging technology, interventional cardiology and image guided surgery and healthcare IT related areas such as PACS, medical information storage, and disaster recovery/business continuance will also be covered. The Health and wellness cluster covers cutting-edge global developments in medical devices and imaging sectors such as biosensors, biomaterials, biomechanics, microtechnologies, nanotechnologies, assistive technologies and imaging technologies and platforms. Keywords: Artificial intelligence, clinical workflow automation, quadripolar CRT leads, gastrointestinal imaging, brain blood flow monitoring device, portable vein viewing device, high-frequency ultrasound Fri, 29 Sep 2017 00:00:00 +0100 Technologies Impacting the Future of Smart Cities http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7F3-01-00-00-00 By 2050, over 80% of the population in developed countries is expected to have moved to cities. This number is expected to be over 60% for the developing world. The creation of smart cities enables a smooth transition to urbanization through the most optimal utilization of resource to maximize value for the participants in the ecosystem. This value may be extrinsic as in financial, or intrinsic such as an improvement in the quality of life, health, convenience, a reduced environmental footprint or savings in time. What are some technologies that will be most impactful to the evolution of smart cities? Although there are many more technologies that impact smart cities than covered in this report, this report has aimed to outline the ten technologies that it believes to be most impactful from a variety of tech spaces. Among these are ADAS, which Distributed energy generation, which leads to much greater efficiencies in energy management Smart glass, which helps to reduce the environmental footprint of a smart city Wearables, which leads to real-time tracking of health and fitness, and improved patient outcomes Personalized Medicine, to move from a one-size-fits-all healthcare model to a more targeted approach High-strength, lightweight materials, which leads to a reduced environmental footprint Robotics, which are expected to increasingly automate dangerous and routine tasks AI, which is expected to create predictive and prescriptive insights from data Small Data, which enables more efficient resource utilization Vertical farming, which will help combat space constraints and weather-related failures Fri, 29 Sep 2017 00:00:00 +0100 Technologies Enabling Super-resolution Biomedical Imaging http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7B5-01-00-00-00 TechVision's latest research service from the medical imaging technology cluster highlights the emerging trends and innovations in super-resolution biomedical imaging. Over the last two decades, powered by rapid advances in electronics and sensors, information technology and telecommunications, microscopes have evolved from moderately powerful, stand-alone imaging devices into powerful, networked and highly-intelligent diagnostic systems. A term that has evolved over the last decade is super-resolution. Super-resolution imaging techniques that are employed to improve the resolution of imaging systems, in an attempt to break the diffraction limit a phenomenon that determines the limitations of optical imaging systems. This research service sheds light on the super-resolution imaging technology landscape, key business and technology considerations that are aiding and hampering market adoption, areas that present opportunities for growth and research activity in this area. Fri, 29 Sep 2017 00:00:00 +0100 Innovations Empowering Social Robots http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7E9-01-00-00-00 Robotics is being adopted globally in various industries for automated applications. Among these robots, social robots play vital role in directly interacting with human beings. These social robots utilize several technologies from cloud computing, touch sensor, motion sensor, servo motors, facial recognition software, 3D cameras, computer chips powerful operating systems and advanced artificial intelligence algorithms to make robots appear and interact more life-like. The research report captures innovations in social robotics which could have applications in healthcare, retail/trade, hospitality and education. Some of the key applications of social robots include childcare, elderly care, interact/assist with customers in retail shops, entertain people in tradeshows/exhibitions, assisting human beings in day-to-day activities, assist hotel guests in delivering products and teach/coach children. Key questions answered in the study: What are social robots? What are the needs for social robots? What are the needs driving innovations in social robots for various applications? What are the factors influencing the development of smart robots? What are the region wise key players? What are the key funding trends witnessed in the social robots space? When is the key impact of social robotics? Fri, 29 Sep 2017 00:00:00 +0100 Artificial Intelligence and Advanced Analytics in Healthcare http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7DF-01-00-00-00 The global healthcare industry is in need of solutions that augment providers with insights to make meaningful clinical decisions within less turnaround times, which is critical to demonstrating value of care. Artificial Intelligence has proven its utility in performing data-mining activities on large sets of patient and population health data, addressing vital gaps in automating the clinical workflow. Adoption of artificial intelligence technologies has reduced healthcare costs by 50%, while improving patient outcome by over 50%. Advanced analytic frameworks evaluate 'unstructured data', such as physician-entered notes, health statistics, clinical literature and radiology reports to deliver trends critical to improving the quality of healthcare. This research service (RS) offers a strategic perspective on the impact of artificial intelligence (AI) and advanced analytics on the global healthcare industry. This RS has been segmented into five chapters, with the first two focusing on analysis of the top trends from both technology and competitive perspectives. the third, fourth and fifth chapters focus on the global adoption landscape, reviewing the roles and strategies of both existing and emerging participants. Key questions answered by this research services (RS): 1. What are the major classes of artificial intelligence and advanced analytics technologies? What are the sub-classification of technologies for various clinical applications by commercial attractiveness and intensity of patenting activities? 2. Who are the key stakeholders within the global healthcare industry, including medical device companies, pharmaceutical companies and biotechnology firms that are pioneering technology development initiatives for driving sustainable market growth efforts across potential markets? 3. What is the role of stakeholders across the value chain and their efforts towards development of technologies? 4. How has the global competitive landscape evolved over the past decade, especially with respect to those innovating artificial intelligence solutions for addressing needs faced by the global healthcare industry? Fri, 29 Sep 2017 00:00:00 +0100 Technology Roadmapping of Micro-LED Displays http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7E6-01-00-00-00 With rapid proliferation of high power applications and features in smart electronic devices, the battery life of such devices is often very low. Display components of smart devices consume majority of the power, thus manufacturers and developers are under constant pressure to develop a next generation innovative display technology to increase the battery life of smart electronic devices and appliances. Micro-LEDs/ m-LED/ LED is a high-brightness low power display technology which is proving to become competitive over conventional displays. Advanced sensing and visible light communication (VLC) are key applications enabled by micro-LED technology. With increase in proliferation of micro-LED technology, sectors such consumer electronics, automobile, and life sciences will have high impact. Government support/initiatives and the huge market potential for display applications can drive advancements and adoption of micro-LEDs in the long term. Micro-LED technology has the ability to replace conventional small, medium, and large displays in the longer term. The technology and innovation report discusses key capabilities and applications of micro-LED technology. The applicability of the technology in the short, medium, and long term is analyzed. Some of the key questions addressed in the report are highlighted below. What is the significance of micro-LED technology? What are the key applications impacted by the technology? What are key factors influencing adoption? Who are the major innovators and innovations? What is the future prospect of the technology? How does patent and funding drive technology development? What sort of strategies would OEMs need to embrace to gain entry and sustain competition? Fri, 29 Sep 2017 00:00:00 +0100 Future Wearables in Healthcare - R&D Portfolio Areas and Technology Roadmapping http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7EB-01-00-00-00 Wearable technologies in healthcare are expected to have key growth opportunities in the next few years driven by factors such as the proliferation of wearables for health and wellness and the need for more data about the current and future condition of individuals and patients. This technology and innovation report provides analysis of key technology innovations and identifies key healthcare wearable device developers in diverse areas such as electronic skin, smart gloves, glucose sweat sensors, wearable stethoscopes, asthma monitoring patches, smart bandages electrocardiogram monitoring, smart clothing. The study also assesses key markets, needs, opportunities, and challenges for healthcare wearable devices. This research aims at providing: A brief snapshot and analysis of R&D opportunities in the domain of healthcare wearables Key innovations based on the opportunities which drive the development of wearables in healthcare sector Key Drivers for the adoption of wearables in healthcare Key Technology Challenges hindering the adoption of wearables in healthcare. Emerging Market Needs Technology Roadmap Strategic insights about market and emerging trends Fri, 29 Sep 2017 00:00:00 +0100 Telehealth: Tomorrow s Breakthrough Challenged by Today s Problems http://www.frost.com/prod/servlet/sublib/display-market-insight.do?id=297913586 Telehealth, sometimes referred to as telemedicine, is a combination of telecommunication services combined with advanced medical device technology and cloud-based platforms used to deliver healthcare to patients not in the same physical location as the provider or care giver. Thu, 28 Sep 2017 00:00:00 +0100 Image Guidance and Navigation Technologies for Robotic Surgery http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7E1-01-00-00-00 The importance of medical imaging has expanded beyond just diagnoses. Increasingly, more imaging modalities are being integrated into therapy systems, and as guidance tools during surgical procedures. TechVision's latest research service from the medical imaging technology cluster highlights the emerging trends and innovations in use of medical imaging for guidance and navigation during surgical procedures and treatments. Two broad application areas have been delineated: image-guide surgery (IGS) and image-guided therapy (IGT). IGS and IGT use medical imaging tools such as x-ray radiology, ultrasound imaging and magnetic resonance imaging (MRI) in guiding the surgeon and the robotic system during surgical procedures. IGS initially found acceptance because it provides guidance to surgeons, which increases precision and accuracy. However, with the advent of surgical robots, it has become a pre-requisite since navigation of tools during minimally-invasive surgeries require real-time visualization. This research service sheds light on the ultrasound technology landscape, key business and technology considerations that are aiding and hampering market adoption, areas that present opportunities for growth and research activity in this area. Thu, 28 Sep 2017 00:00:00 +0100 Impact of Visible Light Communication (VLC) Technology http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7E7-01-00-00-00 Over the past years, globally there has been tremendous transformation in communication and lighting sectors with evolution of advanced and many new technologies such as OLED, Micro-LED, 4G, 5G networks. Smart connected devices have witnessed rapid industrial growth and new technologies and products are constantly on the rise. With the advent of the Internet of Things (IoT), smart homes, automation, connected living communication plays a vital role in driving technology innovations in different industries. LEDs (light emitting diodes) which are commonly used for display and lighting applications is leveraged for wireless data transmission driven by advancements in the optoelectronics sector. The concept of transmitting data through light rays is termed as Visible Light Communication (VLC). There are numerous applications enabled by VLC and these include: consumer electronics, automotive, aerospace and defense, industrial, healthcare, home and building automation. VLC can be useful in applications where RF (radio frequency) communication is difficult to achieve the objective. Ultra-high speed data transmission and high bandwidth capabilities drive the adoption of VLC over other communication platforms. The technology and innovation report captures the impact of VLC on different applications. Key questions answered in the report are highlighted below. 1. What is the significance of VLC? 2. What are the key enabling technologies? 3. What are the factors that influence technology development and adoption? 4. Who are the key innovators driving developments? 5. What are the opportunities based on patent and funding trends? 6. What is the VLC technology adoption by region (North America, Europe, and Asia-Pacific)? 7. What are the applications enabled by VLC technology? 8. What is the market potential for VLC technology (forecast until 2021)? 9. What is the future prospect of the technology? 10. What sort of strategies OEMs need to embrace to gain entry and sustain competition? Thu, 28 Sep 2017 00:00:00 +0100 Italy's New Business Models in Medical Imaging, Forecast to 2021 http://www.frost.com/prod/servlet/sublib/display-report.do?id=MBFA-01-00-00-00 This research study focuses on the drive to operationalize capital and service costs favoring non-conventional business models (MES and MVS) in Italy over traditional capital-intensive purchasing and service models. The study also features a detailed elaboration on the legacy of public-private partnerships (PPP), framework agreement case studies, market opportunity, market size and penetration analysis coupled with merger and acquisitions and the competitive landscape, in addition to growth opportunities. Frost & Sullivan's Definition on MES and MVS for Italy market Managed Equipment Services (MES): This is a bundled solution that includes the purchase of new equipment in addition to basic maintenance and support, technology management, planning and potentially a number of more advanced value-adding services. The bundle is usually financed by the customer through operational expenditure and typically extends, at a minimum, throughout the lifecycle of the equipment (7+ years). Multi-Vendor Services (MVS): This is a vendor-neutral offering combining basic and more advanced services, such as repair and maintenance services in addition to replacement planning (small components in imaging systems) for multimodality imaging fleet. The MVS does not include purchase of new equipment like in MES. The MVS provider can be the OEM of part of the equipment, or a third-party company, and act as a single source for service, working in line with in-house resources at the imaging provider site. Key Market Dynamics: The high cost sensitivity among Italian public healthcare providers and their limited access to capital funding form the key motivation for their consideration to adopt new purchasing and service models for capital imaging equipment. To address the ageing equipment fleet and worsening technology obsolescence situation in the installed bases, different regional communities in Italy are looking closely at the opportunity for framework agreements with industry consortia to provide a viable long-term equipment renewal strategy. Framework agreements involving a multi-vendor consortium represent the majority of market activity in Italy as of 2016. Frost & Sullivan's research on Italy indicates that National and Regional GPOs continue to engage in customer-vendor partnerships amidst growing windows of opportunities by the PPP models. Moving forward, the number of existing and planned public-private partnerships (PPP) for green-field hospital build may offer a strong basis for new capital purchasing models in imaging technology. Thu, 28 Sep 2017 00:00:00 +0100 Data Storage Technologies of the Future http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7D6-01-00-00-00 Data storage technologies (DSTs) are evolving with the exponential rise in the demand for high capacity and secured storage systems in the recent years. This is mainly due to the change in technological perception in the global community which focuses on facilitating simplified interaction with the latest innovations happening around as data forms an integral part of this transformation. From offering high-capacity storage capabilities along with providing secure and advanced data management systems, DSTs will be a driving force for majority of the technological advancements and trends in various industries. Advanced technologies and platforms such as wearable electronics, machine learning, artificial intelligence, IoT, smart factories will be relying completely on the data storage media to generate meaningful output to support decision making. This technology and innovation report offers insights on three prominent technologies which are shaping up the current data storage market along with few application specific case studies which will have impact in the near future. The technologies include innovations and its impact in non-volatile random access memories (NVRAMs), flash memory and cloud storage. NVRAM technology scope comprises assessment of MRAM (Magnetoresistive random-access memory), FRAM (Ferroelectric Random Access Memory), PCM (Phase-change memory), RRAM/ ReRAM (Resistive random-access memory), DRAM (Dynamic random-access memory), and NRAM (Nano random-access memory). Flash memory technology coverage includes 3D NAND and 3DXPoint along with SSDs (solid state drives), NVDIMMs (Non-Volatile Dual In-line Memory Module) and Enterprise flash. Cloud storage involves comparison between various cloud storage architecture like file storage and object storage, public, private and hybrid storage. Key questions answered in the report 1. What is the significance of emerging data storage technologies (DSTs)? 2. What are the key trending applications impacted by DST? 3. What are the innovations in DSTs and its impact in different applications? 4. Who are the major players driving innovation and adoption? 5. What are the key factors influencing adoption? 6. How are patents and funding driving developments and wide spread adoption? 7. What are the key innovation themes? 8. Who has implemented key DSTs and what is the impact? 9. What is the future prospect for DSTs? 10. What will be the key technology in 2022? 11. What are key strategic directions for stakeholders to remain competitive? Wed, 27 Sep 2017 00:00:00 +0100 East African Pharmaceutical Market, Forecast to 2021 http://www.frost.com/prod/servlet/sublib/display-report.do?id=MCFC-01-00-00-00 Pharmaceutical markets in Sub-Saharan Africa are experiencing rapid growth as governments and healthcare providers battle with their respective burdens of disease. The continent has one of the highest burdens of disease, such as HIV, malaria, and tuberculosis, yet has limited healthcare resources and spending. As such there are great opportunities for growth in the pharmaceutical sector. While control and eradication of communicable diseases has been an ongoing priority area for governments, non-communicable diseases have now become an area of concern for the continent. This is driven by various factors that are mentioned in this study. In East Africa, the outlook of the healthcare environment is similar to that of the rest of Africa. The countries generally share similar climate conditions, language, and disease prevalence. While significant strides have been made in healthcare provision, funding, infrastructure development and technology, the pharmaceutical sector in the region as a whole in East Africa is still much smaller than that of other regions in Africa, even though it has a higher population. Significant investments by multinational companies are driving growth using different proven business models. The focus on universal healthcare, providing coverage for each citizen, particularly the poor and vulnerable, is a focal point for governments. With multiple participants in the region, including emerging leaders with high growth rates in the continent, pharmaceuticals in the region will now become more important than ever in the drive for better healthcare and the effort to meet millennium development goals. Some therapeutic areas in the countries under this study are now growing, giving an indication of future pharmaceutical opportunities. The study covers the following pharmaceutical segments: cardiovascular, oncology, respiratory, anti-infective, and central nervous system. Highlights of the report include: Market overview and projections for the pharmaceutical market (2016 2021) Revenue forecast and breakdown by therapeutic area Revenue forecast by country and therapeutic segment analysis Key trends, key participants, participant strategies, competitive environment analysis, and growth opportunities Strategic recommendations and future outlook of pharmaceutical market Key questions this study will answer include: Is the East African pharmaceutical market growing? How long will it continue to grow and at what rate? How is the East African pharmaceutical market structured and who are the key competitors in the market? What are the drivers, restraints, and challenges of the East African pharmaceutical market? How is the regulatory environment in the East African pharmaceutical market, and what is its future impact? Who are the main stakeholders in the East African pharmaceutical market? What are the growth opportunities in the East African pharmaceutical market? Wed, 27 Sep 2017 00:00:00 +0100 Technologies Driving Precision Medicine http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7CB-01-00-00-00 Targeted and personalized therapeutics are likely to transform the existing precision medicine landscape. With recent landmark regulatory approval, CAR T therapy has the potential to emerge as the industry standard for cancer management in the future and potentially replace existing treatment techniques. Bispecific and multi-specific antibody platforms are likely to emerge as the preferred alternatives for existing monotherapy strategies as they offer increased therapeutic efficacy, while reducing off-target effects. This global research service provides comprehensive insights across key technologies, research trends, funding IP outlook, clinical trials and industry innovations that are likely to transform the landscape of chimeric antigen receptor (CAR) T cell and bispecific/multi-specific T cell engaging immunotherapies. Tue, 26 Sep 2017 00:00:00 +0100 US Telemental Health Market, Forecast to 2021 http://www.frost.com/prod/servlet/sublib/display-report.do?id=K203-01-00-00-00 The latest report in the Frost & Sullivan's telehealth series finds that telemental health services and communications enablers are poised to increase in utilization because they offer a therapeutic environment similar to traditional in-person methods, minus the time and costs associated with traveling to a treatment site assuming one is even available. Overall telemental health market revenue is expected to increase at a compound annual growth rate of 22.5% from 2016 to 2021. This report reviews the data that illustrates the magnitude of mental health and substance abuse issues prevalent across the United States coupled with the documented lack of nearby mental health professionals in many locations. The research shows examples of several ongoing programs that have made strides despite a variety of barriers, such as the lack of a standard reimbursement process across states, that must be overcome for these services to achieve their full potential. This report also covers a mix of pure-play telemental health specialists and telehealth companies that have extended their service to include telebehavioral health services, including InSight Telepsychiatry, American Well, Teladoc, MDLIVE , Vidyo, and WeCounsel. Major questions this report will answer include: What are the latest trends impacting the telemental health space? How is the telemental market segmented, and who are the major participants in each segment? What combination of economic supply and demand factors and mental health condition and substance abuse prevalence statistics appear to make the wide-scale adoption of telemental health inevitable? What are the competitive characteristics of the telemental health market, and who are some of the key vendors serving the market and the segments? What is the 5-year revenue outlook for the market and the major segments? Frost & Sullivan found that telemental health services have the potential to become the most successful telehealth application within the next five years. The industry will benefit from the prevalence of mental health and behavioral issues. By 2021, telemental health services will gain recognition as a proven solution to the challenge faced by people who have little or no access to mental health professionals. Tue, 26 Sep 2017 00:00:00 +0100 2017 Customer Attitudes and Adoption Plans of Digital Pathology Technologies http://www.frost.com/prod/servlet/sublib/display-report.do?id=K20A-01-00-00-00 A digital pathology end-user research was conducted to identify trends and developments in the field of digital pathology. The survey sought to collect the key information on usage and adoption and compare the perceptions of current and potential adopters of this technology. For the survey, lab managers and pathologists of pathology facilities were invited to participate in an online survey conducted between June 2017 and July 2017. To qualify for survey participation, respondents had to be working in a private or public laboratory, clinical research institution, reference laboratory, academic medical center laboratory, hospital lab, or diagnostic company that employs digital pathology. Respondents had to be constant users or potential users of this technology. Overall 154 responses were analyzed; more than 77% of the respondents were from the US and nearly 12% were from Europe. A large percent of users are currently using digital pathology tools for research, followed by digital pathology for teaching and education. However, for potential users, automated image analysis topped the list of encouraging areas. It was interesting to note that FDA clearance as a factor did not top the charts in the case of future user. One of the key trends the survey reflected was the transition of digital pathology to cloud pathology, Cloud-based delivery of solutions has proven to decrease burden on IT staff, and is known to reduce installation time and to eliminate the need for costly IT infrastructure. These benefits can truly globalize digital pathology and promote telepathology to a large extent, for a field in which sharing and communication are vital. Nevertheless, Cloud is only a means to deliver the product; the solution must scale, supply a growing set of functionalities, operate with a central cloud infrastructure, and most importantly, provide a HIPAA-compliant and securely accessible environment. Another key trend that emerged was the various criteria required by future adopters of digital pathology. Ease of operation and customer support and training surprisingly led in terms of importance (well ahead of price) during vendor selection; this was a similar trend for current users of digital pathology. Despite some similarities in responses between current and future users, there is significant insight that can be garnered with the differences found between these groups. Mon, 25 Sep 2017 00:00:00 +0100 Breakthroughs in Leveraging Biomarkers for Oncology http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7B2-01-00-00-00 Predictive biomarkers are used to provide the best treatment indication with the greater probability of response to a certain specific chemotherapeutic agent, also considering treatment-related side effects. Prognostic biomarkers are used to identify patients with different clinical outcomes associated with somatic mutations, alterations in DNA methylation, germline polymorphisms, serum cytokine levels, expression of micro-RNA (miRNA) as well as circulating tumor cells (CTCs) in blood. Therefore, the precise identification of highly specific and sensitive biomarkers corresponding to certain clinical outcomes or antitumor effects constitutes one of the most crucial tasks in cancer research and treatment. This research service depicts how biomarkers research has remarkably progressed in oncology and accelerates novel therapeutics discovery and development. In fact, recent biomarker research has outstandingly progressed and assisted early drug discovery and development by providing novel molecular-targeting agents in the field of oncology. Mon, 25 Sep 2017 00:00:00 +0100 Growth Opportunity Assessment of Healthcare IT Market in the United Kingdom, Forecast to 2021 http://www.frost.com/prod/servlet/sublib/display-report.do?id=MD36-01-00-00-00 Key Growth Opportunities in the UK include data sharing and interoperability, cloud, mobility, as well as further new investment in core health IT solutions to best meet the needs of providers in a changing market environment. However, the identification of these Growth Opportunities is only the first step towards succeeding as a vendor in this market. The real demystification lies in understanding very specific target-customer needs and then building a value proposition that addresses those needs. UK, Germany, France and Spain collectively spend over $6 billion on healthcare IT and the regional HCIT adoption stands at almost 80%. The focus of key decision makers in the region will shift from healthcare IT solutions that can capture data to solutions that can enable data sharing and clinical decision support. Between December 2016 and March 2017, Frost & Sullivan conducted a survey of IT managers from 198 hospitals across Western European countries. Findings of the survey were further investigated through in-depth discussions with market vendors and Frost & Sullivan industry thought leaders. Outcomes of the research have been collated into a 4-part series detailing the HCIT landscape across EU4 (The United Kingdom, Germany, France and Spain). Our research found that in spite of a high level of EMR adoption only a little more than 15% of large hospitals share data beyond their organization. This has been a huge detriment to efficient and productive health data utilization across all countries included in this study. However, with changing care paradigms, such as focus on patient-centricity, innovation in care delivery models and the demand for workflow efficiency, improving health data continuity will be a key goal for both governments and providers over the next five years. As a result, interoperability, and standards development and adoption will be major priorities across health systems. Overall, the healthcare IT market in the UK will be driven by eHealth initiatives, changing procurement landscape and emerging digital health platforms that increase collaboration between care segments, enable patient centricity, and encourage high resource utilisation at optimised costs. Vendors will have to consistently demonstrate their core competence by offering hospitals sustainable business models, centred on improved connectivity, accessibility and interoperability of healthcare. Emerging technologies such as cloud, healthcare business intelligence and data analytics will be in demand. This is only a sample of insights that you can gain through our research. Key questions answered in this study include: What are the current trends, challenges and drivers for healthcare IT investment? What will be the most promising growth opportunities and key investment areas over the next five years? How is health IT adoption evolving? What will be the impact and adoption of new technologies? How will these change current industry paradigms and/or bring in new business models? How are the initiatives at the national and the regional level for eHealth adoption impacting the market? What are the current vendor landscape and the tiers of competition in select segments (e.g., Total Health IT, EHR, PCIS)? How are they expected to evolve over the next five years? What do healthcare providers expect when investing in healthcare IT and how has this evolved over the years? What is the forecast for hospital Health IT in the UK until 2021? Mon, 25 Sep 2017 00:00:00 +0100 Growth Opportunity Assessment of Healthcare IT Market in France, Forecast to 2021 http://www.frost.com/prod/servlet/sublib/display-report.do?id=MD75-01-00-00-00 UK, Germany, France and Spain collectively spend more than $6 billion on healthcare information technology (healthcare IT) while regional adoption stands at almost 80%. Healthcare IT markets in these countries are ready to embark upon the next level of digitalisation where providers move from data capturing solutions to those that can derive value from data through improving information sharing, analytics and clinical decision support. France embarked upon the Digital Hospital Strategy as part of its five-year plan (from 2012 to 2017) with the goal of fully digitizing the care delivery system by the end of this period. In spite of a high level of EMR adoption, the country suffers from delays and cost over-runs in comparison to the initial digitalisation plans and intends to rapidly progress towards Stage 5 7 EMRs over the next three years. Integrating care delivery is a key priority for the health system as a whole, which includes developing facets like remote health monitoring, telemedicine, mHealth and IoMT, which enable care delivery outside the hospital. Between December 2016 and March 2017, Frost & Sullivan conducted a survey of IT managers from 198 hospitals across Western European countries. Findings of the survey were further investigated through in-depth discussions with market vendors and Frost & Sullivan industry thought leaders. Outcomes of the research have been collated into a 4-part series detailing the HCIT landscape across EU4 (The United Kingdom, Germany, France and Spain). Our research found that only a little more than 15% of large hospitals across EU share data beyond their organization. This has been a huge detriment to efficient and productive health data utilization across all countries included in this study. However, with changing care paradigms, such as focus on patient-centricity, innovation in care delivery models, and demand for workflow efficiency, improving health data continuity will be a key goal for both governments and providers over the next five years. As a result, interoperability, and standards development and adoption will be major priorities across health systems. France is also targeting improving collaboration and data sharing between healthcare providers and care settings, especially to enable remote care for the elderly and the chronically ill. Inconsistent implementation of initiatives, such as the Dossier Medical Patient (DMP), for establishment of HCIT infrastructure has resulted in fragmented adoption and created complex data silos. To achieve the goal of improving population health, France will need a more harmonized approach to healthcare digitalisation. The eHealth Strategy 2020 has resulted in a business environment conducive to the growth of eHealth vendors. Business models that demonstrate positive clinical and financial outcomes along with partnerships with key stakeholders will be the key to success. Consumers are playing an increasingly evident role in managing their own health. More than 20% of patients in France use connected devices with a high propensity for using them for chronic disease management. France also showcases an unusually high affinity amongst physicians to advocate use of connected devices to support home monitoring. As a result, telehealth technologies and remote care delivery models will emerge as a key growth opportunity and the government is already working towards establishing a regulatory framework that makes sustainable business models through reimbursements possible in this arena. This is only a sample of insights that you can gain through our research. Key questions answered in this study include: What are the current trends, challenges and drivers for healthcare IT investment? What will be the most promising growth opportunities and key investment areas over the next five years? How is health IT adoption evolving? What will be the impact and adoption of new technologies? How will these change current industry paradigms and/or bring in new business models? How are the initiatives at the national and the regional level for eHealth adoption impacting the market? What are the current vendor landscape and the tiers of competition in select segments (e.g., Total Health IT, EHR, PCIS)? How are they expected to evolve over the next five years? What do healthcare providers expect when investing in healthcare? What are the key vendor-/solution-selection criteria of providers while investing in health IT? Mon, 25 Sep 2017 00:00:00 +0100 Technology Innovations for Patient Engagement http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7D0-01-00-00-00 Patient engagement is crucial to better clinical outcomes and a high-performing health system. Patient engagement improves communication between the patients and their care providers, resulting in timely access to healthcare, reduces hospital re-admissions, and enables efficient management of illness. This research service showcases the different technology innovations in patient engagement and how is it impacting the healthcare industry. Digital patient engagement solutions such as use of patient portals, mobile applications, wearables, to even more advanced and emerging technologies such as artificial intelligence, virtual reality and interactive robots and the impact of these technologies on medication adherence, chronic disease or mental health disease management, hospital patient management, population health management, and for pharmaceutical companies are discussed. Mon, 25 Sep 2017 00:00:00 +0100 Growth Opportunity Assessment of Healthcare IT Market in Germany, Forecast to 2021 http://www.frost.com/prod/servlet/sublib/display-report.do?id=MD71-01-00-00-00 UK, Germany, France and Spain collectively spend more than $6 billion on healthcare information technology (healthcare IT), while regional adoption stands at almost 80%. Healthcare IT markets in these countries are ready to embark upon the next level of digitalization where providers move from data capturing solutions to those that can derive value from data through improving information sharing, analytics and clinical decision support. Germany, as a country, is unique due to the early position it took towards enhancing chronic disease management in the country. As of 2017, key Growth Opportunities in the German Healthcare IT market include data sharing and interoperability solutions, cloud platforms, digital mobility, and investments in technologies that support new models of care delivery, like telehealth and telecare. However, the identification of these Growth Opportunities is only the first step towards succeeding as a vendor in this market. The real demystification lies in understanding very specific target customer needs and then building a value proposition that addresses those needs. Between December 2016 and March 2017, Frost & Sullivan conducted a survey of IT managers from 198 hospitals across Western European countries. Findings of the survey were further investigated through in-depth discussions with market vendors and Frost & Sullivan s industry thought leaders. Outcomes of the research have been collated into a 4-part series detailing the HCIT landscape across EU4 (the United Kingdom, Germany, France and Spain). Our research found that despite a high level of EMR adoption, only a little more than 15% of large hospitals share data beyond their organization. This has been a huge detriment to efficient and productive health data utilization across all countries included in this study. However, with changing care paradigms, such as, focus on patient-centricity, innovation in care delivery models, and demand for workflow efficiency, improving health data continuity will be the key goal for both governments and providers over the next five years. As a result, interoperability, and standards development and adoption will be major priorities across health systems. Overall healthcare IT market in Germany will be driven by a need for higher patient-centricity and patient engagement. German consumers are actively involved in self-management of health and wellness, not to mention chronic disease management. People in Germany are health conscious and are willing to invest in Quantified Self solutions. This consumer maturity, combined with the increasing penetration of digital and communication technologies into people s everyday life, is driving them to demand a much greater level of healthcare knowledge and ability to action it themselves and at their convenience. As a result, over the next five years, while hospitals focus on improving the sophistication of the EMR systems, the health system as a whole will invest in patient engagement and patient experience solutions, improved data integration along the care continuum and investments in telehealth and telecare to support chronic disease management. Vendors will have to consistently demonstrate their core competence by offering hospitals sustainable business models, centred around improved connectivity, accessibility and interoperability of healthcare. Emerging technologies, such as cloud, healthcare business intelligence and data analytics, will be in demand. This is only a sample of insights that you can gain through our research. Key questions answered in this study include: What are the current trends, challenges and drivers for healthcare IT investment? What will be the most promising growth opportunities and key investment areas over the next five years? How is health IT adoption evolving? What will be the impact and adoption of new technologies? How will these change current industry paradigms and/or bring in new business models? How are the initiatives at national and regional level for eHealth adoption impacting the market? What are the current vendor landscape and tiers of competition in select segments (e.g., Total Health IT, EHR, PCIS)? How are they expected to evolve over the next five years? What do healthcare providers expect from vendors? What are the key vendor-/solution-selection criteria of providers while investing in health IT? Mon, 25 Sep 2017 00:00:00 +0100 Rapid Charging Technology Empowering Small-Scale Electronics http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7D5-01-00-00-00 With rapid proliferation of smart electronic gadgets and devices in various industries including consumer electronics, healthcare, and automotive, the manufacturers and developers are constantly under pressure to add smart and innovative features to sustain competition. High dependability on smartphones, tablets, laptops, and medical devices, minimizing down time has turned to be a critical aspect of technology development. Rapid/ quick/ fast/ supercharging of electronic devices is gaining momentum among various stakeholders in the electronics ecosystem. Rapid charging can enable charging of devices in few seconds or minutes. Consumer electronics industry is highly competitive and adding features such as rapid charging will create competitive advantage for stakeholders. Smart phones, laptops, wearables, hearing aids/ear phones, cameras, trimmers, EVs will benefit from rapid charging in the medium-long term. The rapid charging technology is poised to impact portable electronics in 2019. By 2021, rapid charging will evolve from being an emerging technology to next generation charging platform for various electronic applications. Strategic alliances (collaboration/partnership/joint venture), technology licensing can drive technology development and adoption in existing and niche market segments. The technology and innovation report discusses the impact of rapid charging on portable electronic devices. Some of the key questions addressed in the report are highlighted below: 1. What is the significance of rapid charging technology? 2. What are the key applications impacted by the technology? 3. What are key factors influencing adoption? 4. Who are the major innovators and innovations? 5. What is the future prospect of the technology? 6. How does patent and funding drive technology development? 7. What sort of strategies OEMs need to embrace to gain entry and sustain competition? Fri, 22 Sep 2017 00:00:00 +0100 Recent Advances in Biopharmaceutical and Precision Medicine Platforms http://www.frost.com/prod/servlet/sublib/display-report.do?id=D758-00-59-00-00 This edition of the Genetic Technology TOE depicts the current landscape and the new life sciences trends across biopharmaceutical and precision medicine platforms. A summary of key clinical trials for Patidegib and Quizartinib therapies is also depicted, along with the industry interactions. The Genetic Technology TechVision Opportunity Engine (TOE) presents the latest R&D developments and advances with an emphasis on opportunities to profit in the explosive field of genetic technology through technology transfer, joint ventures, and acquisitions. The complete gamut of genetic technology applications is covered including the latest developments in omics technologies; genetic, cellular, and alternative therapies; sequencing technologies; and genetically altered animals and plants. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Biopharmaceuticals, precision medicine, genetic disorders, leukemia, enhanced delivery platform, genomics Fri, 22 Sep 2017 00:00:00 +0100 Wearable Technologies and Healthcare: Differentiating the Toys and Tools for Quantified-Self with Actionable Health Use Cases http://www.frost.com/prod/servlet/sublib/display-market-insight.do?id=297865654 One of the most transformative shifts we are starting to see in healthcare is the rise of a concept called Quantified-Self . Digitization of products, services, and commerce models are democratizing current healthcare systems, manifesting a new era of healthcare consumerism. Mon, 18 Sep 2017 00:00:00 +0100 Advances in Knee Implants, ECG monitoring, Remote Monitoring, Cloud Technology, Disposable Surgical Retractors, and Anti-snoring Devices http://www.frost.com/prod/servlet/sublib/display-report.do?id=D852-00-15-00-00 Personalized orthopedic implants, remote cardiac health management, continuous patient monitoring, and sleep management device, are some of the innovations that are profiled in TechVision's latest edition of the Medical Device TOE. These innovations span the breadth of the healthcare industry, and have all been developed by innovative medical device companies, keeping in mind the emerging technology and market trends shaping the industry. The Medical Device TechVision Opportunity Engine (TOE) analyzes and reports on new and emerging technologies and advances in R&D; product development; and regulatory matters related to neurology, ophthalmology, respiratory/anesthesia, wound care and management, surgical tools and instrumentation, drug delivery, orthopedics, endoscopy, cardiology, and monitoring. Medical devices and imaging technology and innovation research covers cutting-edge global developments in medical devices and imaging sectors such as biosensors, biomaterials, biomechanics, microtechnologies, nanotechnologies, assistive technologies, and imaging technologies and platforms. Keywords: 3D printing, personalized healthcare, brain health mapping, healthcare cloud, continuous patient monitoring Fri, 15 Sep 2017 00:00:00 +0100 Emerging Role of Gamma Delta T-cells in Immunotherapies http://www.frost.com/prod/servlet/sublib/display-report.do?id=D835-00-22-00-00 This edition of the Future Tech TOE focuses on the emerging role of gamma delta T-cell platforms in immunotherapy applications. This service provides valuable insights across the global adoptive T-cell therapy landscape, while outlining the key unmet needs across this space. Apart from profiling key innovators in this space, the research encompasses application overview, clinical trial analysis, summary of key technology drivers and challenges, IP overview, research funding scenario, and strategic insights across gamma delta T-cell platforms. The Future Tech TechVision Opportunity Engine (TOE) captures emerging innovations in research and development, or profile existing technologies which have seen a resurgence in terms of new markets and applications. It usually provides a technology overview, drivers, challenges, research and development, analyst insights and key patent information. In some cases, technology convergence scenarios and future growth opportunities are outlined. It covers innovations and technologies in a variety of industry spaces including manufacturing, sensors, electronics, information and communications technologies, networks, lighting technologies, healthcare, medical devices, materials and coatings, and developments in the energy sector that contribute toward a sustainable and greener world. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Chimeric antigen receptor T-cell therapy, gamma delta T-cells, T-cells, adoptive T-cell therapies, cancer immunotherapy, targeted therapy, CAR T therapy Fri, 15 Sep 2017 00:00:00 +0100 Recent Advances in Cancer and Eye Disease Management http://www.frost.com/prod/servlet/sublib/display-report.do?id=D758-00-58-00-00 This edition of the Genetic Technology TOE depicts life sciences trends across cancer and eye disease management. The corresponding clinical trials scenario is depicted along with industry interactions. A summary of key clinical trials using BMS-986016 therapy is also presented. The Genetic Technology TechVision Opportunity Engine (TOE) presents the latest R&D developments and advances with an emphasis on opportunities to profit in the explosive field of genetic technology through technology transfer, joint ventures, and acquisitions. The complete gamut of genetic technology applications is covered including the latest developments in omics technologies; genetic, cellular, and alternative therapies; sequencing technologies; and genetically altered animals and plants. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Eye disorders, cancer, next-generation cancer immunotherapy, immune checkpoint inhibitors, aldehyde trapping platform, oncoprotein candidate Fri, 15 Sep 2017 00:00:00 +0100 BioJapan & Regenerative Medicine Japan 2017 http://www.frost.com/prod/servlet/sublib/display-market-insight.do?id=297847072 BioJapan, Asia s premier partnering event for the global biotechnology industry, has played a vital role in facilitating interaction between biotech-related organizations from Japan and abroad for almost 20 years. As well as a large-scale exhibition and a jam-packed seminar schedule Fri, 8 Sep 2017 00:00:00 +0100 Advances in Drug Discovery and Development http://www.frost.com/prod/servlet/sublib/display-report.do?id=D951-00-15-00-00 This Drug Discovery TechVision Opportunity Engine (TOE) provides insights across research advances in gene editing technologies that have enabled enhanced drug screening and target discovery. Furthermore, the service also includes regulatory advances for 3,4-methlyenedioxymethamaphetamine and Ibrutinib therapies. Interestingly, the TOE encompasses advances in novel target discovery for neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Alzheimer s disease (AD). Lastly, the TOE summarizes key technologies and trends fueling the growing use of Big Data for drug discovery applications. The Drug Discovery TechVision Opportunity Engine (TOE) reports and analyzes about the latest developments in drug discovery and therapeutics, thereby providing an opportunity to acquire strategic insights into crucial developments in this industry domain. Technologies profiled include those used for biomarker and target discovery such as high throughput screening, signal transduction, micro array, RNAi, metabolomics, toxicogenomics, biosensors and nanotechnology. In addition to these, a fair focus shall be dedicated to the latest trends in therapeutic approaches across a diversity of diseases including infectious, genetic, metabolic, neurological, cardiac, and autoimmune disorders. The Health and Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Gene editing, CRISPR, drug discovery, drug screening, cancer immunotherapy, immune checkpoint inhibitor, lentivirus transduction, synthetic lethality, posttraumatic stress disorder, MDMA, chronic graft-versus-host-disease, Imbruvica, tyrosine kinase inhibitor, neurodegenerative diseases, Alzheimer s disease, amyotrophic lateral sclerosis, Big Data, predictive analytics, artificial intelligence, cloud computing Fri, 8 Sep 2017 00:00:00 +0100 Recent Advances in Targeted Therapies http://www.frost.com/prod/servlet/sublib/display-report.do?id=D758-00-57-00-00 This edition of the Genetic Technology TOE depicts trends across targeted therapies. Few important targeted therapy innovations have been presented along with summary of clinical trials for CAR T 19 and CTL019 therapies. The focus of the TOE is on disease screening and management. The corresponding clinical trials scenario is also depicted along with the industry interactions. In particular, clinical trial analysis and industry interactions around CRISPR/Cas-9 gene editing are highlighted. The Genetic Technology TechVision Opportunity Engine (TOE) presents the latest R&D developments and advances with an emphasis on opportunities to profit in the explosive field of genetic technology through technology transfer, joint ventures, and acquisitions. The complete gamut of genetic technology applications is covered including the latest developments in omics technologies; genetic, cellular, and alternative therapies; sequencing technologies; and genetically altered animals and plants. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Targeted therapy, CAR T-cell therapy, FDA approval, Actemra (Tocilizumab), CAR T-cell-induced cytokine release syndrome (CRS), antibody therapeutics, fibrosis Fri, 8 Sep 2017 00:00:00 +0100 Top 5 Reasons Why Every Healthcare Company Should Invest in Blockchain http://www.frost.com/prod/servlet/sublib/display-market-insight.do?id=297840936 One of the monumental shifts we are experiencing in the healthcare industry is the digital decentralization of the care delivery models. Digitization of drugs (therapies), devices, services, and business models are democratizing current healthcare systems, unlocking new values by displacing high-cost gatekeepers and previously inaccessible segments. Tue, 5 Sep 2017 00:00:00 +0100 Innovations in Smart Sensors http://www.frost.com/prod/servlet/sublib/display-report.do?id=D7D7-01-00-00-00 A smart sensor comprises a sensing element, an analog to digital converter (ADC), analog interface circuit and bus interface in a single housing. The smart sensors are built with one or numerous smart functionalities such as self-identification, self-testing, self-validation, and self-adaptation. Smart sensors are applicable for sensing temperature, pressure, humidity, image signals, vibration, and other key parameters depending on the nature of application. Smart sensors are attractive due to their ability to provide real-time measurements of complex phenomena and they make decisions on their own leading to diagnosis and corrective measures. Smart sensors have a very wide range of applications in sectors such as consumer electronics, automotive, aerospace and defence, industrial, healthcare, structural health monitoring and home and building automation. Key industries impacted: Building Automation: Lighting and access control, monitoring HVAC systems, tracking machine health status, climate control systems, power monitoring, data centre monitoring, and fire safety Industrial Control: Asset management, process control and monitoring, environmental care, energy management, and equipment health monitoring/condition-based monitoring Military and Defence: Border protection, perimeter protection, battlefield information and real-time situational awareness Consumer Electronics: Smart television, smartphones, tablets, laptops, personal computers and peripherals Healthcare: Managing patients chronic conditions, smart medical device automation, and early prediction of health problems Structural Health Monitoring: Aerospace structures, composites, geo-technique, mining/oil/gas exploration and production, civil engineering structures, and monuments of cultural heritage Automotive: Parking/reverse assist, night vision, lane departure warning, intelligent adaptive cruise control, and driver fatigue monitoring Key questions answered in the technology and innovation report. 1. What is the technology and market dynamics of smart sensors? 2. What are the key enabling technologies? 3. What are the factors that influence development and adoption? 4. Who are the key innovators driving developments? 5. What are the opportunities based on patent and funding trends? 6. What is the smart sensor adoption by region (North America, Europe, and Asia-Pacific)? 7. What are the applications enabled by smart sensors? 8. What is the impact of applications enabled by smart sensors? 9. What are some of the key interesting developments? 10. Where do we see growth opportunities in smart sensor technology? 11. What is the nature of competition? 12. What is the impact of megatrends? 13. What sort of strategies companies need to embrace to remain competitive? 14. What are key questions for strategy planning? Tue, 5 Sep 2017 00:00:00 +0100 Recent Advances across the Cancer Immunotherapy Landscape http://www.frost.com/prod/servlet/sublib/display-report.do?id=D758-00-56-00-00 This edition of the Genetic Technology TOE depicts trends across cancer immunotherapy. Different innovations and collaborations among the main participants in the field are illustrated. The corresponding clinical trials scenario is depicted, along with the industry interactions. The Genetic Technology TechVision Opportunity Engine (TOE) presents the latest R&D developments and advances with an emphasis on opportunities to profit in the explosive field of genetic technology through technology transfer, joint ventures, and acquisitions. The complete gamut of genetic technology applications is covered including the latest developments in omics technologies; genetic, cellular, and alternative therapies; sequencing technologies; and genetically altered animals and plants. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: Cancer immunotherapy, oncology, immune activator ProTIA Platform, cancer therapy, immune cells Fri, 1 Sep 2017 00:00:00 +0100 Regulatory Question Marks Shed Uncertainty on the US Molecular Imaging and Diagnostic Radiopharmaceutical Industry http://www.frost.com/prod/servlet/sublib/display-market-insight.do?id=297822278 The past few months have placed a cloud of uncertainty over the future of healthcare in the United States. At the time of writing this article, Senate Republicans have failed to secure the necessary votes to pass the Better Care Reconciliation Act (BCRA). Mon, 28 Aug 2017 00:00:00 +0100 Recent Advances across T cell-based Therapeutics http://www.frost.com/prod/servlet/sublib/display-report.do?id=D758-00-55-00-00 This edition of the Genetic Technology TOE depicts trends across T cell-based therapeutics. Novel T cell receptor-based therapeutic platforms and robust T cell target discovery platforms are profiled. The corresponding clinical trials scenario is also depicted, along with industry interactions. The Genetic Technology TechVision Opportunity Engine (TOE) presents the latest R&D developments and advances with an emphasis on opportunities to profit in the explosive field of genetic technology through technology transfer, joint ventures, and acquisitions. The complete gamut of genetic technology applications is covered including the latest developments in omics technologies; genetic, cellular, and alternative therapies; sequencing technologies; and genetically altered animals and plants. The Health & Wellness cluster tracks developments in a myriad of areas including genetic engineering, regenerative medicine, drug discovery and development, nanomedicine, nutrition, cosmetic procedures, pain and disease management and therapies, drug delivery, personalized medicine, and smart healthcare. Keywords: T cell-based therapies, T cell Engager Platform, malignant cells target, dual-affinity re-targeting, cancer disease, autoimmune disease, T cell receptors, T cell target discovery platform Fri, 25 Aug 2017 00:00:00 +0100 Medical Imaging Innovations in Ultrasound Systems, Artificial Intelligence, Endoscopy, OCT, and PET http://www.frost.com/prod/servlet/sublib/display-report.do?id=D861-00-17-00-00 The latest issue of Medical and Diagnostic Imaging Technologies (MDIT) TechVision Opportunity Engine (TOE) profiles innovations in medical and diagnostic imaging. The profiles covered include quantitative tissue assessment using ultrasound, an artificial intelligence-based skin cancer diagnostic tool, an ophthalmic imaging tool for corneal epithelial thickness mapping, a hybrid endoscope for early diagnosis of esophageal cancer, a self-teaching artificial intelligence medical imaging solution, hybrid point-of-care imaging solutions, and a soft tissue surgical site marker . Medical and Diagnostic Imaging TechVision Opportunity Engine (TOE)'s mission is to analyze and report new and emerging technologies; advances in R&D, product development and regulatory matters specifically related to the areas of CT, MRI, NM, PET, Ultrasound and X-ray. In addition, relevant developments in fusion technologies, functional imaging technology, interventional cardiology and image guided surgery and healthcare IT related areas such as PACS, medical information storage, and disaster recovery/business continuance will also be covered. The Health and wellness cluster covers cutting-edge global developments in medical devices and imaging sectors such as biosensors, biomaterials, biomechanics, microtechnologies, nanotechnologies, assistive technologies and imaging technologies and platforms. Keywords: Quantitative tissue assessment, skin cancer diagnostics, epithelial thickness mapping, artificial intelligence, hybrid imaging modalities, surgical site marker, retinal imaging Fri, 25 Aug 2017 00:00:00 +0100 Developments in Image-Guided Therapy, Forecast to 2020 http://www.frost.com/prod/servlet/sublib/display-report.do?id=MD4E-01-00-00-00 Medical imaging and informatics research service from the Transformational Health practice highlights the evolving trends and innovations in Image-Guided Therapy (IGT). As the fields of interventional imaging, minimally-invasive interventions, and image-guided surgery (IGS) continue to mature, the next step forward in the development of advanced treatment procedures is combining image guidance modalities with therapeutic modalities in real time. The emergence of IGT as a growing set of niche procedures is expected to push forward a number of clinical specialties, starting with oncology where it will boost the under-developed field of interventional oncology and in neurology where it will tackle some of the most under-served neurological conditions. Ultrasound shines in the IGT field, both as a guidance or as a treatment modality (focused, high-intensity ultrasound: FUS, HIFU), but virtually every other diagnostic imaging and treatment modality is finding its place in the IGT landscape that is shaping out. For example, as part of the spectrum of emerging IGT procedures is integrated MR-LINAC, which builds further than the current gold standard of image-guided-radiotherapy (IGRT) by providing real-time magnetic resonance image guidance, in a single gantry. This allows for a radiation where the region of interest can be segmented more precisely, the dose delivered and targeted more finely, and the risks of patient movement addressed more effectively. This research sheds light on the IGT technology advances, growth opportunity landscape, and market considerations that are aiding and hampering adoption in the marketplace. Philips Healthcare is clearly capitalising on IGT as a core pillar of its growth strategy in imaging, operating high-profile partnerships, acquisitions, and product launches in this area, and the competitive dynamics are heating up substantially. Key Questions this Study will Answer What are the latest developments in image-guided therapy (IGT) industry? What does the role of advanced imaging look like in present-day interventional and therapeutic applications? How are the multi-modality integration, image fusion, and real-time image guidance technologies shaping up next-generation IGT solutions? What are the new products and solutions launched in the IGT industry? What does the future for IGT look like? What is the future market potential? What are the key market trends? What are the key drivers and restraints impacting the growth opportunities in the global IGT market? What are the top IGT applications gaining significance in the industry? Which are the applications clinically established? What are the applications in exploratory phase? Who are the major market participants? What are their major product offerings? How can the competitive landscape be characterised? Which vendors are dominating the market currently? Tue, 22 Aug 2017 00:00:00 +0100